6-substituted tropinones and their manufacture

  • Inventors:
  • Assignees: Basf Ag
  • Publication Date: March 25, 1981
  • Publication Number: GB-1586793-A


Novel 6- and 8-substituted tropinones of the formula I are prepared from corresponding 3-substituted 2,5-dialkoxytetrahydrofurans. The tetrahydrofurans are first treated with water at a pH of 0 to 3. The resulting treatment mixture is then reacted with a primary amine and with acetone dicarboxylic acid at a pH of 4 to 6. The substituents in formula I have the meaning mentioned in the patent claim. The compounds of the formula I are starting substances for the preparation of colorants, crop protection agents and pharmaceuticals. <IMAGE>




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